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What kind of infusion set filter membrane can prevent the backflow of blood

Issuing time:2023-05-10 15:31

It is very common to use filter membranes in infusion sets, which can filter out particles and bacteria in the liquid, thereby reducing the harm of drugs to patients. The infusion set using the filter membrane can not only better protect the health of the patient, but also improve the efficiency and accuracy of the infusion, and more importantly, ensure that the filter membrane has a better problem of preventing blood backflow.

The hysteresis performance of the membrane.jpg

In order to prevent the blood from flowing back after the liquid is used up, the filter membrane used in the infusion set generally needs to have good hysteresis performance to prevent the liquid from flowing back. For example, some filter membranes specially used in infusion sets use polycarbonate materials, which have good biocompatibility and liquid stagnation properties, and can effectively prevent backflow after the liquid is used up.

Liquid hysteresis, also known as wettability, refers to the contact performance between the surface of an object and a liquid. That is, the expansion of the liquid on the surface of the object can be divided into wettability and non-wettability. Wettability means that the liquid can completely spread on the surface of the object, while non-wettability means that the liquid cannot spread on the surface of the object, showing a certain angle between them. The hysteresis is related to the surface properties and chemical composition of the material.

The difference in the hysteresis performance of the material surface is determined by the energy difference of the surface. If the surface energy of the material is greater than the surface tension of the liquid, the material can effectively spread the liquid and exhibit good hysteresis. Conversely, if the surface energy of the material is less than the surface tension of the liquid, the liquid cannot spread completely across the surface and the material is said to be non-wetting.

In infusion sets, fluid hysteresis is important because fluid needs to flow smoothly through the filter membrane to maximize the filtering effect and prevent contamination and damage to the patient. Therefore, the design of the filter membrane material needs to consider its hysteresis performance to ensure that the liquid can spread smoothly on the surface of the filter membrane and prevent the liquid from flowing back.

what materials have hysteresis properties.jpg

Filtration membrane material with good stagnation performance:

1. Polyimide (PI): This material has excellent mechanical properties and chemical stability, and its surface has a certain degree of hydrophilicity, which can effectively prevent the backflow of liquid.

2. Polytetrafluoroethylene (PTFE): This material has a low coefficient of friction and good surface wettability, so it exhibits low resistance during liquid flow and has good stagnation properties.

3. Polycarbonate (PC): This material has good chemical stability and mechanical strength, and has a certain degree of hydrophilicity, which can make the liquid form a good stagnation effect on the surface of the filter membrane.

4. Cellulose acetate (CA): The surface of this material has a certain hydrophilic property, which can effectively prevent the backflow of liquid, and can reduce the viscosity during the filtration process and improve the accuracy of infusion.

Different materials have different surface energies and chemical structures and thus different hysteresis. For example, materials with biocompatible functional groups such as hydroxyl and amine groups usually have better liquid hysteresis and can effectively prevent backflow.

the principle of hysteresis.jpg

In addition, some special filter membranes, such as hydrolyzed polytetrafluoroethylene (Hydrophilic PTFE) and acrylic polymer (Acrylic Polymer), are also widely used in infusion sets, and these materials can maintain High flow and filtration efficiency, and has good anti-backflow performance.


Citation

1.Amini, M., & Raisi, A. (2019). Fabrication of cellulose acetate membranes with high hysteresis properties using nanostructured hydrophilic silica particles. Chemical Engineering Journal, 372, 700-712.

2.Lee, J. H., Kim, H. Y., & Choi, J. Y. (2017). Effect of surface morphology of poly (vinylidene fluoride) (PVDF) membranes on hysteresis phenomenon during filtration. Chemical Engineering Science, 163, 20-28.

3.Guo, Y., Zhao, L., & Wang, X. (2019). Structural modification of poly (vinylidene fluoride) ultrafiltration membranes by solvent vapor annealing to enhance hysteresis properties. Journal of Membrane Science, 585, 154-163.

4.Jiao, Y., Hu, X., Zhang, Y., & Zhang, W. (2019). Preparation and characterization of a cellulose acetate ultrafiltration membrane with excellent hysteresis properties. Industrial & Engineering Chemistry Research, 58(10), 4128-4137.


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